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  • Diagnostic Performance of Serum miR-586 and miR-493 in Patients with Osteosarcoma
  • Abstract This study aimed to explore the expression and diagnostic performance of miR-586 and miR-493 in patients with osteosarcoma. We enrolled 63 patients with osteosarcoma treated between May 2016 and May 2019 as the experimental group and 55 healthy volunteers who underwent physical examination during the same period as the control group. We detected miR-586 and miR-493 expression in serum, normal bone tissue, and tumor samples. We also evaluated the relationship between clinical indicators and the miR-586 and miR-493 expression levels. The correlation between the serum and osteosarcoma tissue expression of miR-586 and miR-493 was examined by Pearson analysis. Furthermore, the…
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  • Expression Changes, Prognostic Analysis and Risk Factors of miR-625-3p and miR-449a in Osteosarcoma Patients after Surgery
  • Abstract The expression changes of miR-625-3p and miR-449a in osteosarcoma patients after surgery is the critical study in this paper. Analysis of their prognosis and risk factors can be helpful in understanding the prognostic value for clinical purposes. Fifty-eight patients with osteosarcoma diagnosed in our hospital were considered as the research group (RG), and 52 health subjects at the same time were collected as the control group (CG). Fluorescence quantitative PCR (RTPCR) was employed to test the expression levels of miR-625-3p and miR-449a in the serum of subjects in both groups before surgery and patients in the RG after surgery. The…
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  • Sinomenium Inhibits the Viability of Hepatoma Carcinoma Cells through Activating IFNA2
  • Abstract Hepatocellular carcinoma (HCC) ranks the sixth place of most common cancers. Meanwhile, it is the tertiary mortality cause of cancer. There is no effective therapeutic method to prevent and treat the liver cancer. Sinomenine is a kind of Chinese traditional medicine herbal, it is reported that it can inhibit the viability of several cancer cells. The study is to explore whether sinomenine is also able to inhibit the cell viability of HCC and its potential mechanism. The IC50 of sinomenine in BEL-7402 cells was 5.351 mmol/L, and the IC50 of sinomenine in SMMC-7721 cells was 6.204 mmol/L. The gene expression…
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  • Influence of the Molecular Weight on PVA/GO Composite Membranes for Fuel Cell Applications
  • Abstract Composite polymer electrolyte membranes were prepared with poly (vinyl alcohol) (PVA). Two different molecular weight (Mw), 67·103 and 130·103 g·mol−1 were selected, cross-linked with sulfosuccinic acid (SSA) and doped graphene oxide (GO). The effects on the membranes obtained from these polymers were characterized in order to evaluate the fuel cell performance. Electron microscopy showed a proper nanoparticle distribution in the polymer matrix. The chemical structure was evaluated by Fourier transform infrared spectroscopy. The absence of a crystalline structure and the enhancement on the thermal stability with the addition of 1% of GO was demonstrated by thermal characterization. Total transference number…
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  • Dielectric Permittivity of Rigid Rapeseed Oil Polyol Polyurethane Biofoams and Petrochemical Foams at Low Frequencies
  • Abstract Early investigations of dielectric permittivity of rigid polyurethane foams at low frequencies were made on petrochemical-origin foams, mainly by means of parallel plate capacitors. In the present investigation biopolyol was synthesized from Latvia-grown rapeseeds’ oil by the transesterification method with triethanolamine, in an environmentally friendly process, without emission of harmful substances, at temperatures 175°C ± 5°C. Rigid, closed-cell rapeseed oil polyol polyurethane biofoams and petrochemical foams were made ensuring content of the renewable rapeseed oil polyol in ready foams 27 wt.%–29 wt.%. Dielectric permittivity of the polyurethane foams and the underlying monolithic petrochemical-origin polyurethane and biopolyurethane was measured with a…
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  • Improving Interfacial Adhesion of PLA/Lignin Composites by One-Step Solvent-Free Modification Method
  • Abstract To clarify the effects of lignin as a biodegradable filler added into the PLA matrix, PLA/lignin composites with or without silane coupling agent of γ- (2,3-epoxypropoxy)propy trimethoxysilane (KH560) were prepared by a one-step solvent-free modification method. The effects of KH560 as a compatibilizer on the morphology, chemical structure, crystallization behavior, thermal degradative behavior as well as mechanical strength of the PLA/lignin composites were analyzed in detail. It was found that, after modification by KH560, the fractured surfaces of composites became smooth, suggested sufficient bonding between the lignin and PLA in the composites with KH560 coupling agent molecules. This result further…
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  • Green Synthesis of Silver Nanoparticles Using Annona diversifolia Leaf Extract and Their Antimicrobial Application
  • Abstract The aim of this study was the synthesis of silver nanoparticle using Annona diversifolia Safford. The silver nanoparticles obtained were analyzed by spectroscopic methods and dynamic light scattering methods. The inhibition of AgNPs was evaluated against Bacillus cereus, Klebsiella pneumoniae and Enterobacter aerogenes. The results showed that AgNPs have high values at 3 keV and particle size between 45 to 58 nm with a homogenous morphology. The AgNPs showed growth inhibition against Klebsiella pneumoniae and Enterobacter aerogenes. Therefore studies are needed to confirm the potential antimicrobial of different AgNP from A. diversifolia in Gram negative and Gram positive bacteria.
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  • Mechanical Behavior of Light Trusses Made of Poplar Laminated Veneer Lumber and Connected with Bolts and Tooth Plates
  • Abstract Poplar Laminated Veneer Lumber (Poplar LVL) is a new type of engineering materials with high strength, good reliability and small variability. Poplar LVL is manufactured from the fast-growing poplar, which is widely used in packaging, furniture and others, however, is rarely adopted in construction. In order to explore the feasibility of poplar LVL trusses in construction of roof, four 4.5-m-span Fink-and-Howe trusses were designed and assembled, which were made of poplar LVL with bolted- and tooth-plated connections. Vertical static loading on the upper chord joints of a truss was imposed by self-balancing test device. The mechanical properties of trusses were…
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