TY  - EJOU
AU  - Drerup, Jennifer 
AU  - Borsum, Anjali 
AU  - Hayon, Solomon 
AU  - Ziada, Ali 

TI  - Refractory ischemic priapism in adolescents with beta thalassemia trait and sickle cell trait: a two-patient case series
T2  - Canadian Journal of Urology

PY  - 
VL  - 
IS  - 
SN  - 1488-5581

AB  -  <b>Background:</b> Ischemic priapism is an uncommon but urgent condition in pediatric patients and is most frequently associated with sickle cell disease, although other hemoglobinopathies may also contribute to refractory cases. <b>Case Description:</b> Two adolescent males presented with refractory ischemic priapism. Initial management with corporal aspiration and phenylephrine was unsuccessful. Further evaluation identified previously undiagnosed beta thalassemia trait in one patient and sickle cell trait in the other. Both ultimately required surgical shunting with successful detumescence and favorable postoperative outcomes. <b>Conclusions:</b> These cases highlight the importance of considering hemoglobinopathies beyond sickle cell disease and support early hematologic evaluation in recurrent or refractory pediatric priapism.
KW  - ischemic priapism; beta thalassemia; sickle cell trait; pediatric urology; case report

DO  - 10.32604/cju.2026.082281