TY  - EJOU
AU  - Chaudhary, Uzair B. 
AU  - Rashid, Mohammad H. 
AU  - Onitilo, Adedayo A. 
AU  - Bissada, Nabil K. 

TI  - Secondary hormonal manipulations in the management of advanced prostate cancer
T2  - Canadian Journal of Urology

PY  - 2005
VL  - 12
IS  - 3
SN  - 1488-5581

AB  - Prostate cancer is a heterogeneous disease and clinical
outcomes vary considerably after failure of primary
androgen ablation. With the development of new
therapeutics the management of patients with androgen
independent prostate cancer has changed considerably
over the last few years. Multiple secondary hormonal manipulations are available and may lead to prolonged
periods of clinical response. These maneuvers include
the use of oral antiandrogens, antiandrogen withdrawal,
ketoconazole, aminoglutethimide, corticosteroids and use
of estrogenic compounds. This article reviews the clinical
activity of these agents in management of patients with
advanced prostate cancer.
KW  - prostate cancer
KW  -  hormone refractory
KW  -  hormone treatment
KW  -  androgen deprivation
KW  -  antiandrogens
KW  -  steroids

DO  -