TY  - EJOU
AU  - Cox, Ashley 
AU  - Nguan, Christopher Y. 
AU  - Luke, Patrick P. W. 

TI  - Partial nephrectomy for renal cell carcinoma in long-term renal allografts: operative and postoperative considerations
T2  - Canadian Journal of Urology

PY  - 2005
VL  - 12
IS  - 6
SN  - 1488-5581

AB  - The majority of immunosuppressive agents used to
prevent rejection in transplant patients have also been
shown to increase malignancy risk. Renal transplant
patients are dependent upon their solitary allograft
kidneys in order to remain dialysis free, and the discovery
of a primary malignancy within the allograft poses a
therapeutic dilemma. We describe two cases of primary
renal allograft malignancies and discuss nephron-preserving surgical treatment. Furthermore, we discuss
the potential anti-tumor role of the immunosuppressive
agent sirolimus in the treatment of these complex patients.
KW  - renal transplant
KW  -  renal cell carcinoma
KW  -  partial nephrectomy

DO  -