@Article{,
AUTHOR = {Savino M. Di Stasi, Antonella Giannantoni, Robert L. Stephen,
Luigi Storti, Francesco Attisani, Andrea De Carolis,
Guido Virgili},
TITLE = {Percutaneous sequential bacillus CalmetteGuèrin and mitomycin C for panurothelial carcinomatosis},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {12},
YEAR = {2005},
NUMBER = {6},
PAGES = {2895--2898},
URL = {http://www.techscience.com/CJU/v12n6/62506},
ISSN = {1488-5581},
ABSTRACT = {A 59 year old male presented with a 4 month history of
lower urinary tract symptoms.<br/>
Exhaustive urological investigations revealed papillary
tumors and carcinoma in situ extending from the
prostatic urethra, throughout the bladder, up both ureters
and into the renal pelves.<br/>
Tumors were resected where possible and then bacillus
Calmette-Guèrin (BCG) and mitomycin C (MMC)
were infused sequentially through bilateral
nephrostomy tubes for a total of six BCG and three
MMC instillations.<br/>
Follow up 1 month post treatment demonstrated a
complete response which persisted for 2 years. Then there
appeared a solitary papillomatous recurrence in the
bladder which was successfully resected. Side effects were
the occasional fever and BCG induced granulomatis
prostatitis which slowly resolved.<br/>
In conclusion, sequential BCG/MMC instillations were
effective treatment for widespread panurothelial
carcinomatosis.},
DOI = {}
}