TY  - EJOU
AU  - Agarwal, Mayank Mohan 
AU  - Singh, Shrawan K. 
AU  - Acharya, Naveen C. 
AU  - Mete, Uttam K. 
AU  - Mandal, Arup K. 

TI  - Non-interventional management of obstructive acute renal-failure in hormone-naïve prostate cancer
T2  - Canadian Journal of Urology

PY  - 2007
VL  - 14
IS  - 3
SN  - 1488-5581

AB  - Advanced carcinoma prostate (CaP) commonly
presents as bilateral ureteric obstruction. The
management often requires androgen ablation along
with temporary urinary diversion (percutaneous
nephrostomy or ureteric catheterization) which is not
infrequently associated with complications. Two
patients of hormone-naïve CaP presented to our
emergency department with oliguric renal failure due
to bilateral ureteric obstruction and were treated with
dialysis, ketoconazole (for androgen ablation) and
corticosteroids; urinary diversion was not feasible in
either at the time of presentation. Brisk diuresis
occurred within 48 hours obviating the need of urinary
diversion. Follow-up of these cases is presented and
justification of this approach is discussed.
KW  - prostate cancer
KW  -  ketoconazole
KW  -  oliguria orchidectomy

DO  -