@Article{,
AUTHOR = {Yoh Matsuoka, Gaku Arai, Hisashi Ishimaru,
Kentaro Takagi, Yuji Ito},
TITLE = {Primary signet-ring cell carcinoma of the prostate},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {14},
YEAR = {2007},
NUMBER = {6},
PAGES = {3764--3766},
URL = {http://www.techscience.com/CJU/v14n6/62353},
ISSN = {1488-5581},
ABSTRACT = {We report a rare case of primary signet-ring cell
carcinoma of the prostate in an advanced stage.
A 62-year-old man with serum level of prostate-specific
antigen at 364.70 ng/ml was diagnosed as having
cT4N1M1c prostatic signet-ring cell carcinoma
of Gleason score 5 + 4 = 9. Immunohistochemical
examination demonstrated cytoplasmic immunoreactivity
to prostate-specific antigen in signet-ring cancer cells.
The intracytoplasmic vacuoles in the signet-ring cells
showed mucin production with a positive staining with
periodic acid-Schiff. Although the patient received
hormonal therapy, the disease progressed and lead to death
15 months after the diagnosis. The clinical and
immunohistochemical characteristics of this malignancy
are also reviewed.},
DOI = {}
}