@Article{,
AUTHOR = {Harry S. Clarke Jr, Matthew R. Eskridge, Ahmed M. El-Zawahry, Thomas E. Keane},
TITLE = {Salvage cryosurgical ablation of the prostate for local recurrence after radiation therapy: improved outcomes utilizing a capromab pendetide scan and biopsy algorithm},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {14},
YEAR = {2007},
NUMBER = {Suppl.6},
PAGES = {24--27},
URL = {http://www.techscience.com/CJU/v14nSuppl.6/63316},
ISSN = {1488-5581},
ABSTRACT = {<b>Purpose:</b> We assessed the efficacy, complications and technical advancements in salvage cryosurgical ablation of the prostate for recurrent prostate cancer after radiation therapy.<br/>
<b>Methods:</b> A total of 58 patients were evaluated for salvage cryosurgery using an algorithm of capromab pendetide scan and prostate biopsy from January 2003 to July 2007. Forty-seven patients underwent salvage cryosurgery and biochemical recurrence-free survival and complications were retrospectively reviewed. Mean follow-up was 24 months.<br/>
<b>Results:</b> Seventy percent of patients achieved a nadir PSA < 0.5 ng/ml. Overall, 51% of patients achieved a durable PSA response with a pre-salvage serum PSA < 10 predictive of success. There were no major complications and minor complications were few.<br/>
<b>Conclusion:</b> Salvage cryotherapy in experienced hands utilizing third-generation technology provides for excellent biochemical control with minimal morbidity.},
DOI = {}
}