TY - EJOU AU - Jr., Sam D. Graham, AU - Warden, Mary Elizabeth AU - Lou, Jeffrey TI - Molecular targeted therapies for renal cell carcinoma T2 - Canadian Journal of Urology PY - 2007 VL - 14 IS - Suppl.6 SN - 1488-5581 AB - New advances in technology to directly target specific molecular events in the proliferation of cancer have led to promising results in renal cell carcinoma. Response rates in excess of 70% and complete responses in advanced (metastatic) renal cell carcinoma have caused a change in the paradigm of treatment from immunotherapy. Toxicities are significant, but manageable and pushing the toxicity to tolerability may increase the response rate. KW - renal cell carcinoma KW - metastatic KW - therapy KW - molecular DO -