@Article{,
AUTHOR = {Prashant Jani, Ahmed Lotfy Nasr, Dina El Demellawy},
TITLE = {Synchronous renal cell carcinoma and adrenocortical carcinoma: a rare case report and clinicopathologic approach},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {15},
YEAR = {2008},
NUMBER = {2},
PAGES = {4016--4019},
URL = {http://www.techscience.com/CJU/v15n2/62316},
ISSN = {1488-5581},
ABSTRACT = {A case of synchronous adrenocortical carcinoma (ACC)
and renal cell carcinoma (RCC) has not yet been described
in the English medical literature, to our knowledge. We
report a first such case of adrenocortical and renal cell
carcinomas occurring simultaneously in a 53-year-old
male. He presented with history of vague abdominal pain.
Ultrasound followed by a computed tomography (CT)
scan and a magnetic resonance imaging (MRI)
examination revealed a 6.4 cm left adrenal mass and a
3.5 cm right renal mass. The patient had complaints of
gastroparesis manifesting with constant nausea as well
as intermittent abdominal bloating and abdominal pain.
He also had history of profuse intermittent sweating.
There was no history of palpitations or fluctuations in
blood pressure. The patient's urinary vanillylmandelic
acid (VMA) levels and serum cortisol levels were
normal. His 24-hour urine metanephrine levels were
slightly elevated. Left adrenalectomy and right partial
nephrectomy were performed. In this case, it is important
to determine whether these tumors represent metastases
or two synchronous tumors, as this has implications on
the patient’s management and prognosis. Clinical and
pathological clues that led to the diagnosis are discussed
in detail.},
DOI = {}
}