
@Article{,
AUTHOR = {Yoh Matsuoka, Makoto Hirokawa, Kimio Chiba,
Takafumi Hashiba, Takeshi Tomoda, Shimpei Sugiura},
TITLE = {Biphasic and monophasic sarcomatoid carcinoma of the urinary bladder},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {15},
YEAR = {2008},
NUMBER = {3},
PAGES = {4106--4108},
URL = {http://www.techscience.com/CJU/v15n3/62296},
ISSN = {1488-5581},
ABSTRACT = {We report a rare case of sarcomatoid carcinoma of the 
urinary bladder which showed both of biphasic and 
monophasic phenotypes through its clinical course. 
A 64 year-old man presented with gross hematuria 
and interrupted voiding. Radiological examination 
demonstrated a pedunculated tumor in the bladder 
with no distant metastases. Pathological diagnosis of 
transurethral resection revealed biphasic sarcomatoid 
carcinoma, pT1, composed of squamous cell carcinoma 
component and spindle cell component. The disease 
had repeated local recurrences and partial and total 
cystectomies were performed consequently. The recurrent 
tumors were monophasic sarcomatoid carcinoma purely 
composed of spindle cell component. The patient died 
of local and metastatic disease 13 months after the 
diagnosis. We consider that sarcomatoid carcinoma 
should be resected radically at the initial surgical 
treatment because of aggressive potential of spindle cell 
component. To our knowledge, this is the fi rst case in 
which biphasic sarcomatoid carcinoma of the bladder 
recurred as monophasic tumor. The pathological study 
and management of this neoplasm are discussed, and the 
literature is reviewed.},
DOI = {}
}



