@Article{,
AUTHOR = {Imre Romics, Eszter Székely, Attila Szendröi},
TITLE = {Signet-ring cell carcinoma arising from the urinary bladder},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {15},
YEAR = {2008},
NUMBER = {5},
PAGES = {4266--4268},
URL = {http://www.techscience.com/CJU/v15n5/62257},
ISSN = {1488-5581},
ABSTRACT = {<b>Introduction:</b> Signet-ring cell carcinoma of the urinary bladder can be primary — arising from the bladder wall or urachus remnants — or metastatic from tumors originating in the stomach, colon, or breast. Saphir first described primary signet-ring cell cancer of the urinary bladder in 1955. Less than 100 cases have been reported in the literature since then.<br/>
<b>Case report:</b> We report a case of a 45-year-old woman who was admitted with gross hematuria. Cystoscopy revealed a necrotic tumor on the left bladder wall. A transurethral biopsy showed signet-ring cell carcinoma. The bladder tumor was diagnosed as the primary one. Radical cystectomy was performed with ureterosigmoidostomy (Mainz pouch II). Histological examination showed a primary signet-ring cell carcinoma of the bladder (pT3bN0M0). Following surgery, the patient received adjuvant chemotherapy with cisplatin and fluorouracil.<br/>
<b>Conclusions:</b> Primary signet-ring cell carcinoma of the urinary bladder is an extremely rare tumor, accounting for approximately 0.24% of all bladder malignances. Patients with this type of cancer generally have a poor prognosis. However, our patient is free of disease 5 years after radical cystectomy.},
DOI = {}
}