TY  - EJOU
AU  - Dangle, Pankaj P. 
AU  - Wang, Wenle Paul 
AU  - Pohar, Kamal S. 

TI  - Vesicoenteric, vesicovaginal, vesicocutaneous fistula –an unusual complication with  intravesical mitomycin
T2  - Canadian Journal of Urology

PY  - 2008
VL  - 15
IS  - 5
SN  - 1488-5581

AB  - Intravesical instillation of mitomycin C is a routine practice 
for treatment of superfi cial transitional cell carcinoma of 
bladder. Despite usual precautions serious side effects 
like fi stulation can occur with diverse presentation as 
illustrated by this report. The pathology demonstrates 
a dense necrotic and massive infl ammatory reaction in 
the peri vesical tissue following the extravasation of an 
intravesically administered chemotherapeutic agent. The 
severe infl ammatory tissue response and the necrotic effect 
associated with the extravasated chemotherapeutic agent 
could potentially lead to local sepsis with a subsequent 
fi stula formation.
KW  - fistulation
KW  -  delayed presentation
KW  -  intravesical instillation of chemotherapy

DO  -