
@Article{,
AUTHOR = {Dina El Demellawy,
Ahmed Nasr,
Salem Alowami,
Nicholas Escott},
TITLE = {Enteric type urachal adenocarcinoma: a case report},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {16},
YEAR = {2009},
NUMBER = {4},
PAGES = {4753--4756},
URL = {http://www.techscience.com/CJU/v16n4/62157},
ISSN = {1488-5581},
ABSTRACT = {Urachal pathology is rare. The most frequently reported 
lesion is urachal adenocarcinoma. The pathogenesis of 
urachal adenocarcinoma is unknown. We report a case 
of a 55-year-old man who presented with microscopic 
hematuria. Clinical work up showed a tumor involving 
the urinary bladder with extravesical extension. Masses 
or tumors involving other organs were excluded. Partial 
cystectomy revealed a distended bladder wall with the 
formation of a cystically dilated mass fi lled with mucoid 
material. Microscopic examination showed enteric type 
adenocarcinoma with abundant mucin formation. The 
neoplastic urachal epithelium showed features of colonic 
differentiation as evidenced by the presence of goblet cells 
and positive staining for acid mucin and cytokeratins 
20 (CK 20). Such features are absent in non-neoplastic 
urachal epithelium. This was a rare case of urachal 
adenocarcinoma, enteric type, with abundant mucin 
formation. The urachal adenocarcinoma had morphological 
features and an immunohistochemical profi le that were 
similar to that of adenocarcinoma of the colon.},
DOI = {}
}



