@Article{,
AUTHOR = {Jack Barkin},
TITLE = {Benign prostatic hyperplasia and lower  urinary tract symptoms: evidence and  approaches for best case management},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {18},
YEAR = {2011},
NUMBER = {Suppl.2},
PAGES = {14--19},
URL = {http://www.techscience.com/CJU/v18nSuppl.2/63031},
ISSN = {1488-5581},
ABSTRACT = {Significant lower urinary tract symptoms (LUTS) are 
very common in men over age 50. It is appropriate for the 
primary care physician to perform the work up to confirm 
that benign prostatic hyperplasia (BPH) is causing the 
LUTS. If the physician determines that the patient has 
moderate symptoms (an International Prostate Symptom 
Score [IPSS] ≥ 8), moderate “bother” (≥ 3 on the IPSS 
“bothersome index” question), and an enlarged (> 30 cc) 
prostate, then the most effective treatment is combination 
therapy with an alpha blocker and 5-alpha reductase 
inhibitor (5-ARI) at the time of confirmed BPH diagnosis. 
This combination will provide the most dramatic, early 
symptom response, the most sustained symptom response, 
and the most durable, reliable prevention of long term 
sequelae (acute urinary retention or the need for surgery), 
if the patient is compliant with taking the combination 
therapy.},
DOI = {}
}