@Article{,
AUTHOR = {Joshua P. Holstead, B. Jill Williams, Alex Gomelsky},
TITLE = {Long term follow up of bovine dermis pubovaginal slings},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {20},
YEAR = {2013},
NUMBER = {2},
PAGES = {6721--6725},
URL = {http://www.techscience.com/CJU/v20n2/61629},
ISSN = {1488-5581},
ABSTRACT = {<b>Introduction:</b> Women with risk factors for surgical failure (advanced age, failed previous anti-incontinence surgery, intrinsic sphincter deficiency, and absence of urethral hypermobility) underwent acellular bovine dermis slings. We evaluate long-term outcomes and complications with this material.<br/>
<b>Materials and methods:</b> We retrospectively identified 41 women who completed 36-month postoperative follow-up. Preoperative evaluation included pelvic exam, SEAPI classification, and validated quality of life (QoL) questionnaires. Stress urinary incontinence (SUI) cure was defined as SEAPI (S) subset = 0 and negative cough-stress test. Perioperative data was abstracted from the hospital and office chart.<br/>
<b>Results:</b> The SUI cure rate was 80.5%. Most SUI recurrences occurred within the first 12 months of follow-up. Perioperative complications and rates of reoperation for recurrent SUI were low. There was a postoperative improvement in mean SEAPI scores and significant improvement in all QoL indices over preoperative baseline values.<br/>
<b>Conclusions:</b> At long-term follow-up, bovine dermis continues to be a durable biologic option for a population at “high risk” for surgical failure after sling surgery. SUI-specific clinical outcomes remain stable, while rates of complications continue to be low. Improvement in QoL indices persists with long-term follow-up.},
DOI = {}
}