@Article{,
AUTHOR = {Scott M. Norberg, Michelle Oros, Varsha Manucha, 
Daniel Eun, Marijo Bilusic},
TITLE = {Loss of e-cadherin and retinoblastoma genes in a case of urothelial carcinoma with scrotal metastasis},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {22},
YEAR = {2015},
NUMBER = {2},
PAGES = {7755--7757},
URL = {http://www.techscience.com/CJU/v22n2/61292},
ISSN = {1488-5581},
ABSTRACT = {Cutaneous metastases from urologic cancers are very 
uncommon, usually represent widespread metastatic 
disease and are associated with a very poor prognosis. 
They may occur in 1% of patients with urologic 
malignancies, most commonly from kidney, followed by 
bladder and prostate tumors. In this report, we describe 
a case of urothelial carcinoma with metastases to the 
scrotum treated with platinum based chemotherapy with 
a durable complete response lasting more than 14 months. 
Molecular profiling revealed deleterious mutations in 
e-cadherin and retinoblastoma genes, suggesting their 
possible role in the pathogenesis of cutaneous metastases. 
Further studies are needed to validate this observation.},
DOI = {}
}