TY - EJOU AU - Baird, Bryce A. AU - Lyon, Timothy D. AU - Wu, Kevin AU - Anderson, Augustus AU - Broderick, Gregory A. TI - Complete pathologic response of bulbar urethral squamous cell carcinoma in situ to topical 5-fluorouracil with urethral milking T2 - Canadian Journal of Urology PY - 2022 VL - 29 IS - 2 SN - 1488-5581 AB - Primary urethral carcinoma is a rare oncologic condition with limited data to support organ-sparing therapies. Herein, we present a case of primary urethral squamous cell carcinoma in situ of the bulbar urethra treated with intraurethral 5-fluorouracil (5-FU) who exhibited a complete pathologic response observed at the time of dismembered urethroplasty. The clinical features, diagnosis, and treatment course of our case are reviewed. These data may support the use of intraurethral 5-FU for similar cases in the future. KW - squamous cell carcinoma KW - urethra KW - urethroplasty KW - primary urethral carcinoma DO -