@Article{,
AUTHOR = {Leslie M. Peard, Belinda Li, Stacy Dorris, Shilin Zhao, Cyrus Adams, Douglass B. Clayton, John C. Thomas, John C. Pope IV, Mark C. Adams, John W. Brock III, Abby S. Taylor},
TITLE = {Are children with food allergies more likely to have lower urinary tract symptoms? A case-control study},
JOURNAL = {Canadian Journal of Urology},
VOLUME = {31},
YEAR = {2024},
NUMBER = {2},
PAGES = {11840--11846},
URL = {http://www.techscience.com/CJU/v31n2/59598},
ISSN = {1488-5581},
ABSTRACT = {<b>Introduction:</b> There are multiple historic reports linking
lower urinary tract symptoms (LUTS) in children with
food allergies (FA), but contemporary studies are sparse.
The objective of this study was to evaluate a potential
link between FA and LUTS in the pediatric population.
We hypothesized that children with FAs are more likely
to have LUTS.<br/>
<b>Materials and methods:</b> After local IRB approval,
pediatric patients (6-17 years [y]) with FAs proven by
positive skin prick and/or serum IgE testing were invited to
participate. A control group of pediatric patients without
FAs was also recruited. All families/legal guardians
signed informed consent, and all children signed written
assent. Each participant filled out the Vancouver Symptom Score (VSS), a validated questionnaire for
dysfunctional elimination syndrome, and the Pediatric
Incontinence Questionnaire (PinQ), a validated quality
of life assessment for children with bladder dysfunction.
Demographic and clinical information were obtained
retrospectively.<br/>
<b>Results:</b> From 2019-2020, 26 children with FAs and 57
without agreed to participate. Mean age was 9.3 y (IQR
7.9 y-13.5 y). There were no differences in gender, age, or
race between the two cohorts. There were no significant
differences between the two groups in mean VSS score or
mean PinQ score. Four children with FAs (15%) and 15
children without (26%) had VSS score ≥ 11 (p = 0.339),
indicating dysfunctional elimination. The median PinQ
score was 0 (IQR 0-2) in both cohorts.<br/>
<b>Conclusions:</b> This study did not identify an association
between FAs and LUTS in a population of pediatric
patients with laboratory proven FAs.},
DOI = {}
}