TY  - EJOU
AU  - Murányi, Mihály 
AU  - Domoszlai, András 
AU  - Nagy, Attila Csaba 
AU  - Flaskó, Tibor 

TI  - Comparing functional outcomes of glansectomy with or without glans reconstruction
T2  - Canadian Journal of Urology

PY  - 2025
VL  - 32
IS  - 2
SN  - 1488-5581

AB  -  <b>Introduction:</b> We aimed to compare the oncological and functional outcomes of glansectomy and split-thickness skin graft reconstruction (GR) with those of glansectomy alone (GA) and penile amputation (PA). <b>Materials and Methods:</b> This retrospective study included patients with penile carcinoma or penile intraepithelial neoplasia diagnosed between 2017 and 2022. Surgical outcomes, complications, and oncological outcomes were assessed through a chart review, and functional outcomes were assessed using a questionnaire administered to patients who underwent GR (group A), GA (group B), or PA (group C). <b>Results:</b> Six, eight, and seven patients were enrolled in groups A, B, and C, respectively. Their complication rates were 0%, 25%, and 29%, respectively; margin positivity rates were 17%, 13%, and 0%, respectively; and local recurrence rates were 0%, 0%, and 14%, respectively. Logistic regression analysis showed that being in group A rather than C was a significant predictor of favorable erectile function (<i>p</i> = 0.007) and cosmetic outcomes (<i>p</i> = 0.030). However, being in group A rather than B was not a significant predictor of favorable erectile function (<i>p</i> = 0.127) or cosmetic outcomes (<i>p</i> = 0.638). <b>Conclusion:</b> Excellent functional results were observed after GR; however, the benefits were significant only when compared with those of amputation.
KW  - penile cancer; organ-sparing treatments; split-thickness skin graft; glansectomy; glans reconstruction

DO  - 10.32604/cju.2025.063821