TY - EJOU AU - Gilmartin, Brian AU - O’Meara, Sorcha AU - Horan, Michelle AU - D’Arcy, Frank T. AU - Dowling, Catherine M. TI - The cost burden of radiation cystitis presentations and investigations T2 - Canadian Journal of Urology PY - 2025 VL - 32 IS - 4 SN - 1488-5581 AB - Background: Radiation cystitis is a well-known complication resulting from radiotherapy for pelvic malignancies. It remains a challenging condition to treat and is associated with significant morbidity for patients. We aimed to establish the economic cost burden of presentations and investigations associated with radiation cystitis over a two-year period to a tertiary referral hospital in Ireland. Materials and Methods: A retrospective review of patient charts was performed for radiation cystitis-related presentations and investigations over 24 months. Costs were estimated in consultation with the hospital finance department and using Health Service Executive data on diagnostic-related groups and average inpatient bed day costs. Results: A total of 56 individual patients were identified over 2 years. 91% male, 9% female. The mean age was 72 years. Twenty-three patients (41%) required inpatient care. Radiation cystitis accounted for 621 inpatient bed days. Median length of stay was 7.5 days. The inpatient care cost was approximately €545,238 (801,908 Canadian dollars (CA$)) over 2 years. Conclusion: Radiation cystitis accounts for a significant amount of inpatient bed days. A conservative estimate of the overall cost burden for inpatient care and outpatient investigations exceeds €280,000 (CA$411,810) per year. KW - radiation cystitis; radiotherapy; complication; cost DO - 10.32604/cju.2025.065805