@Article{cmes.2021.017404,
AUTHOR = {Magdalini Ntetsika, Panayiotis Papadopoulos},
TITLE = {A Hybrid Immersed Boundary/Coarse-Graining Method for Modeling Inextensible Semi-Flexible Filaments in Thermally Fluctuating Fluids},
JOURNAL = {Computer Modeling in Engineering \& Sciences},
VOLUME = {129},
YEAR = {2021},
NUMBER = {3},
PAGES = {1243--1258},
URL = {http://www.techscience.com/CMES/v129n3/45687},
ISSN = {1526-1506},
ABSTRACT = {A new and computationally efficient version of the immersed boundary method, which is combined with the
coarse-graining method, is introduced for modeling inextensible filaments immersed in low-Reynolds number
flows. This is used to represent actin biopolymers, which are constituent elements of the cytoskeleton, a complex network-like structure that plays a fundamental role in shape morphology. An extension of the traditional
immersed boundary method to include a stochastic stress tensor is also proposed in order to model the thermal
fluctuations in the fluid at smaller scales. By way of validation, the response of a single, massless, inextensible
semiflexible filament immersed in a thermally fluctuating fluid is obtained using the suggested numerical scheme
and the resulting time-averaged contraction of the filament is compared to the theoretical value obtained from the
worm-like chain model.},
DOI = {10.32604/cmes.2021.017404}
}