TY  - EJOU
AU  - Mei, Yue 
AU  - Deng, Jianwei 
AU  - Zhao, Dongmei 
AU  - Xiao, Changjiang 
AU  - Wang, Tianhang 
AU  - Dong, Li 
AU  - Zhu, Xuefeng 

TI  - Toward Improved Accuracy in Quasi-Static Elastography Using Deep Learning
T2  - Computer Modeling in Engineering \& Sciences

PY  - 2024
VL  - 139
IS  - 1
SN  - 1526-1506

AB  - Elastography is a non-invasive medical imaging technique to map the spatial variation of elastic properties of soft tissues. The quality of reconstruction results in elastography is highly sensitive to the noise induced by imaging measurements and processing. To address this issue, we propose a deep learning (DL) model based on conditional Generative Adversarial Networks (cGANs) to improve the quality of nonhomogeneous shear modulus reconstruction. To train this model, we generated a synthetic displacement field with finite element simulation under known nonhomogeneous shear modulus distribution. Both the simulated and experimental displacement fields are used to validate the proposed method. The reconstructed results demonstrate that the DL model with synthetic training data is able to improve the quality of the reconstruction compared with the well-established optimization method. Moreover, we emphasize that our DL model is only trained on synthetic data. This might provide a way to alleviate the challenge of obtaining clinical or experimental data in elastography. Overall, this work addresses several fatal issues in applying the DL technique into elastography, and the proposed method has shown great potential in improving the accuracy of the disease diagnosis in clinical medicine.
KW  - Nonhomogeneous elastic property distribution reconstruction; deep learning; finite element method; inverse problem; elastography; conditional generative adversarial network

DO  - 10.32604/cmes.2023.043810