TY - EJOU AU - Hameed, Madiha AU - Zameer, Aneela AU - Raja, Muhammad Asif Zahoor TI - A Comprehensive Systematic Review: Advancements in Skin Cancer Classification and Segmentation Using the ISIC Dataset T2 - Computer Modeling in Engineering \& Sciences PY - 2024 VL - 140 IS - 3 SN - 1526-1506 AB - The International Skin Imaging Collaboration (ISIC) datasets are pivotal resources for researchers in machine learning for medical image analysis, especially in skin cancer detection. These datasets contain tens of thousands of dermoscopic photographs, each accompanied by gold-standard lesion diagnosis metadata. Annual challenges associated with ISIC datasets have spurred significant advancements, with research papers reporting metrics surpassing those of human experts. Skin cancers are categorized into melanoma and non-melanoma types, with melanoma posing a greater threat due to its rapid potential for metastasis if left untreated. This paper aims to address challenges in skin cancer detection via visual inspection and manual examination of skin lesion images, processes historically known for their laboriousness. Despite notable advancements in machine learning and deep learning models, persistent challenges remain, largely due to the intricate nature of skin lesion images. We review research on convolutional neural networks (CNNs) in skin cancer classification and segmentation, identifying issues like data duplication and augmentation problems. We explore the efficacy of Vision Transformers (ViTs) in overcoming these challenges within ISIC dataset processing. ViTs leverage their capabilities to capture both global and local relationships within images, reducing data duplication and enhancing model generalization. Additionally, ViTs alleviate augmentation issues by effectively leveraging original data. Through a thorough examination of ViT-based methodologies, we illustrate their pivotal role in enhancing ISIC image classification and segmentation. This study offers valuable insights for researchers and practitioners looking to utilize ViTs for improved analysis of dermatological images. Furthermore, this paper emphasizes the crucial role of mathematical and computational modeling processes in advancing skin cancer detection methodologies, highlighting their significance in improving algorithmic performance and interpretability. KW - Medical image; skin cancer classification; skin cancer segmentation; international skin imaging collaboration; convolutional neural network; deep learning DO - 10.32604/cmes.2024.050124