TY - EJOU AU - Singhal, Amit AU - Agrawal, Krishna Kant AU - Quezada, Angeles AU - Aguiñaga, Adrian Rodriguez AU - Jiménez, Samantha AU - Yadav, Satya Prakash TI - Explainable Artificial Intelligence (XAI) Model for Cancer Image Classification T2 - Computer Modeling in Engineering \& Sciences PY - 2024 VL - 141 IS - 1 SN - 1526-1506 AB - The use of Explainable Artificial Intelligence (XAI) models becomes increasingly important for making decisions in smart healthcare environments. It is to make sure that decisions are based on trustworthy algorithms and that healthcare workers understand the decisions made by these algorithms. These models can potentially enhance interpretability and explainability in decision-making processes that rely on artificial intelligence. Nevertheless, the intricate nature of the healthcare field necessitates the utilization of sophisticated models to classify cancer images. This research presents an advanced investigation of XAI models to classify cancer images. It describes the different levels of explainability and interpretability associated with XAI models and the challenges faced in deploying them in healthcare applications. In addition, this study proposes a novel framework for cancer image classification that incorporates XAI models with deep learning and advanced medical imaging techniques. The proposed model integrates several techniques, including end-to-end explainable evaluation, rule-based explanation, and user-adaptive explanation. The proposed XAI reaches 97.72% accuracy, 90.72% precision, 93.72% recall, 96.72% F1-score, 9.55% FDR, 9.66% FOR, and 91.18% DOR. It will discuss the potential applications of the proposed XAI models in the smart healthcare environment. It will help ensure trust and accountability in AI-based decisions, which is essential for achieving a safe and reliable smart healthcare environment. KW - Explainable artificial intelligence; artificial intelligence; XAI; healthcare; cancer; image classification DO - 10.32604/cmes.2024.051363