TY - EJOU AU - Ghorbal, Anis Ben AU - Grine, Azedine AU - Eid, Marwa M. AU - El-Kenawy, El-Sayed M. TI - Greylag Goose Optimization and Deep Learning-Based Electrohysterogram Signal Analysis for Preterm Birth Risk Prediction T2 - Computer Modeling in Engineering \& Sciences PY - 2025 VL - 144 IS - 2 SN - 1526-1506 AB - Preterm birth remains a leading cause of neonatal complications and highlights the need for early and accurate prediction techniques to improve both fetal and maternal health outcomes. This study introduces a hybrid approach integrating Long Short-Term Memory (LSTM) networks with the Hybrid Greylag Goose and Particle Swarm Optimization (GGPSO) algorithm to optimize preterm birth classification using Electrohysterogram signals. The dataset consists of 58 samples of 1000-second-long Electrohysterogram recordings, capturing key physiological features such as contraction patterns, entropy, and statistical variations. Statistical analysis and feature selection methods are applied to identify the most relevant predictors and enhance model interpretability. LSTM networks effectively capture temporal patterns in uterine activity, while the GGPSO algorithm finetunes hyperparameters, mitigating overfitting and improving classification accuracy. The proposed GGPSO-optimized LSTM model achieved superior performance with 97.34% accuracy, 96.91% sensitivity, 97.74% specificity, and 97.23% F-score, significantly outperforming traditional machine learning approaches and demonstrating the effectiveness of hybrid metaheuristic optimization in enhancing deep learning models for clinical applications. By combining deep learning with metaheuristic optimization, this study contributes to advancing intelligent auto-diagnosis systems, facilitating early detection of preterm birth risks and timely medical interventions. KW - Preterm birth prediction; electrohysterogram signals; LSTM; time-series analysis; metaheuristic optimization; auto-diagnosis; clinical decision support DO - 10.32604/cmes.2025.068212