TY - EJOU AU - Zhang, Yongjie AU - Wang, Wenyan AU - Liang, Xinghua AU - Bazilevs, Yuri AU - Hsu, Ming-Chen AU - Kvamsdal, Trond AU - Brekken, Reidar AU - Isaksen, Jørgen TI - High-Fidelity Tetrahedral Mesh Generation from Medical Imaging Data for Fluid-Structure Interaction Analysis of Cerebral Aneurysms T2 - Computer Modeling in Engineering \& Sciences PY - 2009 VL - 42 IS - 2 SN - 1526-1506 AB - This paper describes a comprehensive and high-fidelity finite element meshing approach for patient-specific arterial geometries from medical imaging data, with emphasis on cerebral aneurysm configurations. The meshes contain both the blood volume and solid arterial wall, and are compatible at the fluid-solid interface. There are four main stages for this meshing method: 1) Image segmentation and geometric model construction; 2) Tetrahedral mesh generation for the fluid volume using the octree-based method; 3) Mesh quality improvement stage, in which edge-contraction, pillowing, optimization, geometric flow smoothing, and mesh cutting are applied to the fluid mesh; and 4) Mesh generation for the blood vessel wall based on the boundary layer generation technique. The constructed meshes are extensively employed in a fully-coupled fluid-structure interaction analysis of vascular blood flow. This paper presents several case studies of hemodynamics in patient-specific cerebral aneurysms. KW - Tetrahedral meshing KW - fluid-structure interaction KW - cerebral aneurysm DO - 10.3970/cmes.2009.042.131