@Article{cmes.2010.060.151,
AUTHOR = {J.A.Ferreira, P.  Oliveira, P.M.  Silva, A.  Carreira, J.N.  Murta},
TITLE = {Sustained Drug Release from Contact Lenses},
JOURNAL = {Computer Modeling in Engineering \& Sciences},
VOLUME = {60},
YEAR = {2010},
NUMBER = {2},
PAGES = {151--180},
URL = {http://www.techscience.com/CMES/v60n2/25512},
ISSN = {1526-1506},
ABSTRACT = {This paper focuses on the release of an ophthalmic drug (flurbiprofen) from a loaded copolymer where the drug is simultaneously dispersed in the polymeric matrix and entrapped in particles.
The copolymer is based in 2-hydroxyethyl methacrylate co-methacrylic acid and silicone is used to prepare the loaded particles. A mathematical model to simulate the drug release is proposed and a qualitative analysis is performed. In vitro experimental results are compared with simulation results. Contact lens made from the presented copolymer are expected to deliver drug at therapeutical levels for a few days.},
DOI = {10.3970/cmes.2010.060.151}
}