TY - EJOU AU - Ferreira, J.A. AU - Oliveira, P. de AU - Silva, P. AU - Murta, J.N. TI - Drug Delivery: From a Contact Lens to the Anterior Chamber T2 - Computer Modeling in Engineering \& Sciences PY - 2011 VL - 71 IS - 1 SN - 1526-1506 AB - Mathematical models to describe drug concentration profiles of topically administered drug in the anterior chamber aqueous humor have been proposed by several authors. The aim of this paper is to present a mathematical model to predict the drug concentration in the anterior chamber when a therapeutical contact lens with the drug entrapped in nanoparticles is used. KW - Ophthalmic contact lens KW - nanoparticles KW - polymeric matrix KW - cornea KW - anterior chamber KW - diffusion DO - 10.3970/cmes.2011.071.001