@Article{,
AUTHOR = {Robert P. Numerof, Charles A. Dinarello, Khusru Asadullah},
TITLE = {Cytokines as potential therapeutic targets for inflammatory skin diseases},
JOURNAL = {European Cytokine Network},
VOLUME = {16},
YEAR = {2005},
NUMBER = {2},
PAGES = {101--103},
URL = {http://www.techscience.com/ECN/v16n2/66221},
ISSN = {1952-4005},
ABSTRACT = {A network of pro-inflammatory cytokines is a central feature in the pathophysiology of cutaneous
inflammatory diseases. Thus, the delineation of precise roles for particular cytokines and the development of
cytokine-directed therapeutics have become areas of intense investigation. While anti-TNF therapeutics have
proven to be effective for the treatment of psoriasis, clinical investigations have now begun with other
cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that
target cytokines directly, strategies that target cytokine signaling pathways are in development too. In this short
review, we summarize key findings from a recent workshop on cytokines as potential therapeutic targets for
inflammatory skin diseases.},
DOI = {}
}