@Article{ecn.2009.0167,
AUTHOR = {Enrico Crivellato, Beatrice Nico, Domenico Ribatti},
TITLE = {Mast cell contribution to tumor angiogenesis: a clinical approach},
JOURNAL = {European Cytokine Network},
VOLUME = {20},
YEAR = {2009},
NUMBER = {4},
PAGES = {197--206},
URL = {http://www.techscience.com/ECN/v20n4/65889},
ISSN = {1952-4005},
ABSTRACT = {Mast cells (MCs) are tissue leukocytes that are distributed throughout the major organs of the
body. They are an important local source of preformed and newly synthesized angiogenic molecules. MCs have
been linked both to inflammatory and tumor angiogenesis. Indeed, numerous solid tumors and hematological
malignancies present MC-rich infiltrates, which are believed to contribute to the formation of a new vascular
supply. In addition, angiogenesis and MC density have been shown to increase simultaneously with the pathological
progression in many of such tumors. This review will focus on the angiogenic potential of MCs in
human solid and hematological tumors.},
DOI = {10.1684/ecn.2009.0167}
}