@Article{ecn.2011.0286,
AUTHOR = {Ali Hossein Mesgarzadeh, Ali Akbar Abolfathi, Saeed Dastgiri, Maghsod Shaaker, Amir Mansour Vatankhah, Shiva Solehakahnamoiee, Masoud Darabi},
TITLE = {Interleukin-1 beta, interleukin-6 and TGF-beta in follicular tissue of impacted third molars},
JOURNAL = {European Cytokine Network},
VOLUME = {22},
YEAR = {2011},
NUMBER = {2},
PAGES = {103--106},
URL = {http://www.techscience.com/ECN/v22n2/65823},
ISSN = {1952-4005},
ABSTRACT = {The clinical evaluation and management of impacted third molars remain challenging. The aim of
the present study was to investigate possible associations between follicular tissue cytokines and radiographic
manifestations of impacted third molar. The population included 72 patients who underwent surgical extraction of
impacted third molars. All these patients underwent a preliminary panoramic radiograph. Levels of interleukin-1
beta (IL-1β), interleukin-6 (IL-6) and transforming growth factor beta (TGF-β) in tissue extracts were determined
using ELISA. There were no significant differences between bony and tissue impaction as regards IL-1β, IL-6
and TGF-β levels. Moreover, the same results were obtained as far as the amount of pericoronal space and the
presence or absence of a history of pericoronitis are concerned. These results suggest that radiographic findings
or a history of pericoronitis are not associated with levels of expression of pro-inflammatory cytokines in patients
undergoing surgical removal of impacted third molars. However, further studies are needed to address the possibility
of variability during disease progression.},
DOI = {10.1684/ecn.2011.0286}
}