@Article{ecn.2013.0327,
AUTHOR = {Moustafa Hamze, Caroline Desmetz, Paul Guglielmi},
TITLE = {B cell-derived cytokines in disease*},
JOURNAL = {European Cytokine Network},
VOLUME = {24},
YEAR = {2013},
NUMBER = {1},
PAGES = {20--26},
URL = {http://www.techscience.com/ECN/v24n1/65678},
ISSN = {1952-4005},
ABSTRACT = {B cells regulate immune responses during infectious, inflammatory and autoimmune diseases. Beside
their unique and characteristic antibody production, B lymphocytes can modulate physiological and pathological
processes by presenting antigens or synthesizing signaling molecules. In human and mouse diseases, immunointervention,
targeting B cells, has revealed and highlighted their antibody-independent regulatory contribution. In
this review, we focus on B cell-cytokine production, which is commonly disturbed in inflammatory disorders, and
describe the B cell cytokine profile in different diseases. Finally, we discuss some key issues for future B cell-targeted
therapies.},
DOI = {10.1684/ecn.2013.0327}
}