@Article{ecn.2013.0339,
AUTHOR = {Dilek Sarici, Mustafa Ali Akin, Selim Kurtoglu, Ali Yikilmaz, Sabahattin Muhtaroglu, Mehmet Adnan Ozturk, Tamer Gunes, S. Umit Sarici},
TITLE = {Investigation into the relationship between cord blood adiponectin levels and aortic intima media thickness in healthy, term neonates},
JOURNAL = {European Cytokine Network},
VOLUME = {24},
YEAR = {2013},
NUMBER = {2},
PAGES = {104--109},
URL = {http://www.techscience.com/ECN/v24n2/65635},
ISSN = {1952-4005},
ABSTRACT = {Introduction: Adiponectin has important anti-inflammatory and anti-atherogenic effects. Although
adiponectin and atherosclerosis correlate inversely in children and adults, we have little information regarding this
relationship in neonates. Methods: We measured cord blood adiponectin levels and abdominal aortic intima media
thickness (aIMT) in 80 healthy, term neonates and investigated the relationship between adiponectin and total
cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), and triglyceride, and their relationships
to infant anthropometry and gender. Results: Mean birth weight, length, head circumference and aIMT values
for male neonates were statistically significantly higher than those for female neonates. Adiponectin levels were
not significantly different with respect to gender. In correlation analysis, the mean adiponectin level correlated
positively with TC, HDL-C and LDL-C levels and birth weight, length and head circumference. There was no
significant correlation between aIMT and any other parameters. Conclusion: The cord blood adiponectin and
aIMT values reported here for the first time, represent reference values in the early neonatal period. The positive
correlations between adiponectin levels and birth weight, length and head circumference, and TC, HDL-C and
LDL-C indicate that further studies are required to demonstrate the exact relationship and clinical importance of
adiponectin metabolism during the neonatal period.},
DOI = {10.1684/ecn.2013.0339}
}