@Article{ecn.2014.0349,
AUTHOR = {Ewa Ziemann, Robert A. Olek, Tomasz Grzywacz, Jan J. Kaczor, Jędrzej Antosiewicz, Wojciech Skrobot, Sylwester Kujach, Radosław Laskowski},
TITLE = {Whole-body cryostimulation as an effective way of reducing exercise-induced inflammation and blood cholesterol in young men},
JOURNAL = {European Cytokine Network},
VOLUME = {25},
YEAR = {2014},
NUMBER = {1},
PAGES = {14--23},
URL = {http://www.techscience.com/ECN/v25n1/65564},
ISSN = {1952-4005},
ABSTRACT = {Inflammation may accompany obesity and a variety of diseases, or result from excessive exercise. The
aim of this study was to investigate the anti-inflammatory effect of whole-body cryostimulation on the inflammatory
response induced by eccentric exercise under laboratory conditions. The study also sought to establish if cold
treatment changes the lipid profile and modifies energy expenditure in young people. Eighteen healthy and physically
active, college-aged men volunteered to participate in the experiment. They were divided into two subgroups: CRY-submitted
to whole-body cryostimulation, and CONT- a control group. Both groups performed eccentric work to
induce muscle damage. Blood samples were collected before and 24 h after the exercise. Over the five days that
followed, the CRY group was exposed to a series of 10 sessions in a cryogenic chamber (twice a day, for 3 min, at a
temperature of -110℃). After this period of rest, both groups repeated a similar eccentric work session, following
the same schedule of blood collection. The perceived pain was noted 24h after each session of eccentric workout.
A 30-minute step up/down work-out induced delayed-onset muscle soreness in both groups. The five-day recovery
period accompanied by exposure to cold significantly enhanced the concentration of the anti-inflammatory cytokine
IL-10. It also led to a pronounced reduction in levels of the pro-inflammatory cytokine IL-1β, and reduced muscle
damage. The values for IL-10 before the second bout of eccentric exercise in the CRY group were 2.0-fold higher in
comparison to baseline, whereas in the CONT group, the concentration remained unchanged. Furthermore, blood
concentrations of the pro-inflammatory cytokine IL-1β fell significantly in the CRY group. The main finding of this
study was that a series of 10 sessions of whole body cryostimulation significantly reduced the inflammatory response
induced by eccentric exercise. The lipid profile was also improved, but there was no effect on energy expenditure
during the exercise.},
DOI = {10.1684/ecn.2014.0349}
}