@Article{ecn.2018.0403,
AUTHOR = {Yaelle Elfassy, Chloe McAvoy, Soraya Fellahi, Joëlle Dupont, Bruno Fève, Rachel Levy, Jean-Philippe Bastard},
TITLE = {Seminal plasma adipokines: involvement in human reproductive functions},
JOURNAL = {European Cytokine Network},
VOLUME = {28},
YEAR = {2017},
NUMBER = {4},
PAGES = {141--150},
URL = {http://www.techscience.com/ECN/v28n4/65512},
ISSN = {1952-4005},
ABSTRACT = {Infertility, which increased worldwide over the past few decades, has recently been linked to obesity
prevalence. Adipokines, produced by adipose tissue, could be the link between obesity and infertility. The association
between circulating adipokines and female infertility has been extensively studied in the last ten years. However,
the male aspect has been less investigated, although some adipokines are present in seminal plasma. We have
attempted to analyze published studies that measured seminal plasma adipokines and their relationships with
semen parameters. Apart from leptin, other seminal adipokines have rarely been studied. Indeed, leptin seems
to have a differential role depending on its concentration in the seminal plasma. Thus, it could have a beneficial
effect at lower concentrations but a deleterious effect at higher seminal levels. Although some studies are currently
available, the roles of leptin and other adipokines in seminal plasma on sperm parameters and their consequences
on male fertility remain to be clarified.},
DOI = {10.1684/ecn.2018.0403}
}