TY  - EJOU
AU  - Karczewski, Jacek 
AU  - nska, Ewelina Śledzi´ 
AU  - Baturo, Alina 
AU  - Jończyk, Izabela 
AU  - Maleszko, Aleksander 
AU  - Samborski, Paweł 
AU  - Begier-Krasińska, Beata 
AU  - Dobrowolska, Agnieszka 

TI  - Obesity and inflammation
T2  - European Cytokine Network

PY  - 2018
VL  - 29
IS  - 3
SN  - 1952-4005

AB  - The prevalence of obesity has recently increased dramatically and has contributed to the increasing
prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease,
asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence
points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as
a primary force contributing to the development of these pathologies. A better understanding of the underlying
mechanisms behind obesity-induced adipose tissue inflammation is required to develop effective therapeutic or
prophylactic strategies. This review is aimed to present the current knowledge of adipose tissue inflammation
associated with obesity.
KW  - obesity
KW  -  inflammation
KW  -  adipose tissue
KW  -  insulin resistance

DO  - 10.1684/ecn.2018.0415