TY  - EJOU
AU  - Breville, Gautier 
AU  - Lascano, Agustina M. 
AU  - Roux-Lombard, Pascale 
AU  - Lalive, Patrice H. 

TI  - IL-8 as a potential biomarker in Guillain-Barre Syndrome
T2  - European Cytokine Network

PY  - 2019
VL  - 30
IS  - 4
SN  - 1952-4005

AB  - This pilot study was designed to compare the levels of interleukin-8 (IL-8), a pro-inflammatory
chemokine, in the cerebrospinal fluid (CSF) of patients with Guillain-Barre syndrome (GBS), chronic inflammatory
demyelinating polyneuropathy (CIDP), non-inflammatory polyneuropathy (PNP), and other non-inflammatory
neurological diseases (functional syndrome or migraine). The results show elevated CSF IL-8 levels in GBS compared
to the other groups (p < 0.05). IL-8 could be considered a potential biomarker to differentiate GBS from CIDP. This
distinction could be relevant in terms of therapeutic decisions and functional prognosis.
KW  - cytokine
KW  -  chemokine
KW  -  inflammation
KW  -  cerebrospinal fluid
KW  -  chronic inflammatory demyelinating polyneuropathy

DO  - 10.1684/ecn.2019.0436