@Article{ecn.2020.0444,
AUTHOR = {Eda Dokumacioglu, Hatice Iskender, Arzu Sahin, Emine Yurdakul Erturk, Ozgur Kaynar},
TITLE = {Serum levels of nesfatin-1 and irisin in obese children},
JOURNAL = {European Cytokine Network},
VOLUME = {31},
YEAR = {2020},
NUMBER = {1},
PAGES = {39--43},
URL = {http://www.techscience.com/ECN/v31n1/65378},
ISSN = {1952-4005},
ABSTRACT = {Background: Along with the developing technology in the modern age, physical activity had decreased considerably in children and adolescents alike with a concomitant and rapid increase in the prevalence of childhood obesity. The purpose of the present study is to measure the levels of serum nesfatin-1 and irisin in obese children. Methods: The present study was carried out with a total of 62 children, including 32 obese children diagnosed between June 2017 and October 2017 and 30 healthy children. Serum nesfatin-1, irisin, SOD, MDA, fasting blood glucose, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, aspartate amino transferase (AST), alanine amino transferase (ALT), blood urea nitrogen (BUN), C-reactive protein (CRP), calcium (Ca), sodium (Na), potassium (P), chromium (Cr), ferritin, and vitamin B12 data were collected for each patient. Results: In our study, mean nesfatin-1 and SOD values of the obesity group were lower than those of the control group (p < 0.05, p < 0.001), whereas irisin and MDA values were higher than those of the control group (p < 0.001). Conclusion: Childhood obesity is still a significant global problem, despite increased social awareness and numerous preventive healthcare interventions. We believe that all the prospective studies to be carried out to evaluate the relationship between obesity-irisin-nesfatin-1 triad, will make positive contributions to treatment of obesity.},
DOI = {10.1684/ecn.2020.0444}
}