TY - EJOU AU - Zeng, Yezi AU - Cong, Yufei TI - Challenge and Hindrance Academic Stressors and University Students’ Well-Being: The Chain Mediating Roles of Meaning in Life and Academic Self-Efficacy T2 - International Journal of Mental Health Promotion PY - 2025 VL - 27 IS - 11 SN - 2049-8543 AB - Background: Academic stress is a critical factor influencing university students’ well-being. However, research has shown that stress is not a unidimensional construct; different types of stressors (challenge vs. hindrance) may lead to distinct outcomes. This study constructed a structural equation model (SEM) to examine the relationships between challenge and hindrance academic stressors and students’ well-being, as well as the mediating mechanisms. Methods: Data were collected from 836 undergraduates at six universities in China (58.4% female, 41.6% male; Mean age = 20.47 ± 1.46 years). Descriptive statistics, Pearson correlations, and SEM with 5000 bootstrap resamples were conducted to test hypothesized paths and mediating effects. Results: Direct path analysis revealed that challenge stressors positively predicted meaning in life (β = 0.329, p < 0.001) but not academic self-efficacy (β = –0.004, p = 0.915), while hindrance stressors negatively predicted meaning in life (β = –0.371, p < 0.001). Meaning in life strongly predicted academic self-efficacy (β = 0.543, p < 0.001) and well-being (β = 0.301, p < 0.001), and academic self-efficacy further contributed to well-being (β = 0.190, p < 0.001). Bootstrapping confirmed that meaning in life significantly mediated the effects of both challenge (β = 0.099, 95% CI [0.063, 0.144]) and hindrance stressors (β = –0.112, 95% CI [–0.162, –0.076]) on well-being. The serial mediation pathway was also significant for both models (challenge: β = 0.034, 95% CI [0.019, 0.049]; hindrance: β = –0.038, 95% CI [–0.057, –0.024]). Conclusions: This study partially validates the dual-pathway model of academic stress in higher education and highlights the pivotal roles of meaning in life and academic self-efficacy in the stress–well-being relationship. KW - Challenge-hindrance academic stressors; well-being; meaning in life; academic self-efficacy; undergraduates; structural equation modeling DO - 10.32604/ijmhp.2025.072125