@Article{biocell.2007.31.375,
AUTHOR = {JOÃO PAULO MARDEGAN ISSA, RODRIGO TIOSSI, MAMIE MIZUSAKI IYOMASA},
TITLE = {Morphological and histochemical study of the masseter muscle after occlusal alteration},
JOURNAL = {BIOCELL},
VOLUME = {31},
YEAR = {2007},
NUMBER = {3},
PAGES = {375--382},
URL = {http://www.techscience.com/biocell/v31n3/33987},
ISSN = {1667-5746},
ABSTRACT = {The aim of this study was to evaluate alterations in the masseter muscle of 30 male guinea-pigs
submitted to occlusal alteration. The animals were divided into 2 equal groups, the control group (C) only
submitted to surgical stress, and the occlusal altered group (T) submitted to teeth extraction. Each group was
subdivided into 3 groups, with 5 animals, for the following studies: macroscopy and vessels distribution,
light microscopy and histochemical analysis, with animals’ perfusion 2 months after surgery. Data were submitted to statistical analysis. Macroscopically, an anteroposterior orientation of the muscular fibers was found
and statistical difference between C and T groups in width (p<0.05). Microscopically, C and T groups showed
polygonal muscular fibers with variable diameters, and on the left side of the T group these differences were
more pronounced. Histochemically, in both groups, the prevalence of intermediate reactivity fibers and several high reactivity fibers spread out in the deeper area was observed, with no significant differences between
superficial fibers on both sides of C and T groups. It was possible to conclude that the masseter muscle in
guinea-pigs was sensible to functional chewing alteration.},
DOI = {10.32604/biocell.2007.31.375}
}