@Article{biocell.2019.08522,
AUTHOR = {Mohammed Fadhil HADDAD, Tugba DAYIOGLU, Barbaros NALBANTOĞLU, Turgay CAKMAK},
TITLE = {Long term diazotrophic cultivation induces phycobiliprotein production in <i>Anabaena variabilis</i> IMU8},
JOURNAL = {BIOCELL},
VOLUME = {43},
YEAR = {2019},
NUMBER = {4},
PAGES = {327--333},
URL = {http://www.techscience.com/biocell/v43n4/38133},
ISSN = {1667-5746},
ABSTRACT = {Cyanobacteria are considered as a sustainable feedstock for the production of biochemically active
compounds such as phycobiliproteins (PBPs). In this study, the impact of nitrogen (N) and phosphorus (P) availability
on PBP production of “N-free acclimated” <i>Anabaena variabilis</i> IMU8 was analyzed. Upon isolation and identification,
the cyanobacterium has been maintained in N-free BG-11 medium for more than 20 months. For experimentation, the
strain was incubated in N-replete, N-depleted, N-P-depleted BG-11 medium. Long-term diazotrophic cultivation of <i>A.
variabilis</i> IMU8 resulted in elevated PBP productivity with a limited impact on growth. When compared to N-depleted
ones, N supply stimulated a slight induction of growth and total saccharide production, but total protein content did
not change while PBP production decreased. On the other hand, N-P-depletion resulted in decreased growth rate along
with reduced total protein and PBP production while rapid induction of total saccharide production was recorded.
Fourier transform infrared spectroscopy results refer that membrane-bound oligosaccharides may have regulatory roles
for PBP production in <i>A. variabilis</i> IMU8 during long term diazotrophic cultivation.
},
DOI = {10.32604/biocell.2019.08522}
}