TY - EJOU AU - WANG, YONGLU AU - YOU, WEI AU - LI, XUEMING TI - Current status of gene therapy in melanoma treatment T2 - BIOCELL PY - 2020 VL - 44 IS - 2 SN - 1667-5746 AB - Melanoma is the deadliest type of skin cancer and which has a high ability of metastasis. Surgery is an effective method to treat I or II stage melanoma patients. However, there are few treatment options for metastatic melanoma. Gene therapy is one of the attractive options and is considered as the future direction for treating melanoma. This review mainly discusses the properties and challenges of the various gene therapies in melanoma, especially the delivery systems and gene targeting. KW - Gene therapy KW - Melanoma KW - Viral delivery system KW - Nanoparticles DO - 10.32604/biocell.2020.09023