TY - EJOU AU - SHARMA, YASHVI AU - GUPTA, SUCHI AU - MOHANTY, SUJATA TI - Mesenchymal stem cell-derived exosome as a nano weapon to target the COVID-19 pandemic T2 - BIOCELL PY - 2021 VL - 45 IS - 3 SN - 1667-5746 AB - In these times of despair when a nano-sized organism, the SARS-CoV-2, has rendered the human race helpless, made the global health status decline, and drowned the world economy, a ray of hope comes from another nano-sized particle, the exosome. The potential of mesenchymal stem cells has already been established in COVID-19; however, cell-based therapy has its risks. We thereby propose cell-free therapy using stem cells-derived exosomes to fight against COVID-19, as they can be a game-changer owing to their immunomodulatory nature, which combats the cytokine storm characterizing this disease, and their practical efficiency, which will realistically aid large access to therapy worldwide. KW - SARS-CoV-2 KW - Wharton’s Jelly KW - COVID-19 KW - Cell-free therapy KW - Exosomes KW - Immunomodulation DO - 10.32604/biocell.2021.014621