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Exendin-4 inhibits the survival and invasiveness of two colorectal cancer cell lines via suppressing GS3Kβ/β-catenin/NF-κB axis through activating SIRT1

ATTALLA F. EL-KOTT1,2,*, AYMAN E. EL-KENAWY3, EMAN R. ELBEALY4, ALI S. ALSHEHRI1, HEBA S. KHALIFA2, MASHAEL MOHAMMED BIN-MEFERIJ5, EHAB E. MASSOUD6,7,8, AMIRA M. ALRAMLAWY9

1 Biology Department, College of Science, King Khalid University, Abha, 61413, Saudi Arabia
2 Zoology Department, College of Science, Damanhour University, Damanhour, 22511, Egypt
3 Pathology Department, College of Medicine, Taif University, Taif, 11099, Saudi Arabia
4 Biology Department, College of Science for Girls, King Khalid University, Abha, 61413, Saudi Arabia
5 Biology Department, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, 84428, Saudi Arabia
6 Biology Department, Faculty of Science and Arts, Dahran Aljnoub, King Khalid University, Abha, 61413, Saudi Arabia
7 Research Center for Advanced Materials Science, King Khalid University, Abha, 61413, Saudi Arabia
8 Agriculture Research Centre, Soil, Water and Environment Research Institute, Giza, 12619, Egypt
9 Mansoura Research Centre for Cord Stem Cell (MARC-CSC), Stem Cells Bank, Children’s Hospital, Mansoura University, Mansoura, 35516, Egypt

* Address correspondence to: Attalla F. El-Kott, email

TSP_BIOCELL_15464.pdf

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