@Article{biocell.2021.017607,
AUTHOR = {PENGFEI ZHANG, SHAOPENG WANG},
TITLE = {Real-Time analysis of exosome secretion of single cells with single molecule imaging},
JOURNAL = {BIOCELL},
VOLUME = {45},
YEAR = {2021},
NUMBER = {6},
PAGES = {1449--1451},
URL = {http://www.techscience.com/biocell/v45n6/44266},
ISSN = {1667-5746},
ABSTRACT = {The exosome-mediated response can promote or restrain the diseases by regulating the intracellular pathways, making the exosome become an effective marker for diagnosis and therapeutic control at the single-cell level. However, real-time analysis is hard to be achieved with traditional approaches because the exosomes usually need to be enriched by ultracentrifugation for a measurable signal-to-noise ratio. Recently developed label-free single-molecule imaging approaches may become an real-time quantitative tool for the analysis of single exosomes and related secretion behaviors of single living cells owing to their extreme sensitivity.},
DOI = {10.32604/biocell.2021.017607}
}