TY  - EJOU
AU  - ZHANG, PENGFEI 
AU  - WANG, SHAOPENG 

TI  - Real-Time analysis of exosome secretion of single cells with single molecule imaging
T2  - BIOCELL

PY  - 2021
VL  - 45
IS  - 6
SN  - 1667-5746

AB  - The exosome-mediated response can promote or restrain the diseases by regulating the intracellular pathways, making the exosome become an effective marker for diagnosis and therapeutic control at the single-cell level. However, real-time analysis is hard to be achieved with traditional approaches because the exosomes usually need to be enriched by ultracentrifugation for a measurable signal-to-noise ratio. Recently developed label-free single-molecule imaging approaches may become an real-time quantitative tool for the analysis of single exosomes and related secretion behaviors of single living cells owing to their extreme sensitivity.
KW  - Plasmonic scattering; Label-free; Single molecule imaging; Cell secretion

DO  - 10.32604/biocell.2021.017607