@Article{biocell.2021.016484,
AUTHOR = {REKHA GAHTORI, MOSLEH MOHAMMAD ABOMUGHAID, NIDHI NEGI, SARAVANAN KRISHNAN, SUGAPRIYA DHANASEKARAN, SOUMYA PANDIT, KANU PRIYA, DILLIP KUMAR BISHI, RAM PRASAD, PIYUSH KUMAR GUPTA},
TITLE = {Delineating the role of phytocompounds against anti-bacterial drug resistance–An update},
JOURNAL = {BIOCELL},
VOLUME = {45},
YEAR = {2021},
NUMBER = {6},
PAGES = {1465--1477},
URL = {http://www.techscience.com/biocell/v45n6/44278},
ISSN = {1667-5746},
ABSTRACT = {Antibacterial resistance developed by bacteria due to the unlimited use of antibiotics has posed a challenge for
human civilization. This kind of problem is not limited to India only, but it is a global concern. Nowadays, many
treatments and medicines for bacterial diseases have been developed. However, they possess some drawbacks.
Therefore, the alternative medicine has been used to target the drug resistant mechanisms and such medicines have
less side effects which is becoming necessary. Natural products have traditionally or historically been of importance
for the development of antibacterial agents and are also known to overcome bacterial drug resistance by directly
targeting the drug resistance mechanisms in bacteria. In recent years, researchers have also focused on new drug
discovery from plant-based research. They have looked on various phytocompounds as antibacterial agents. In the
current review, we report various classes of secondary metabolites such as phenolic compounds, flavonoids, alkaloids,
saponins, terpenes, quinones, and some essential oils that have been used as an antibacterial agent. In addition, we
also discuss several mechanisms behind bacterial multi-drug resistance that are used during bacterial pathogenesis.},
DOI = {10.32604/biocell.2021.016484}
}