TY  - EJOU
AU  - HUANG, XIAO 
AU  - YU, ZHIHAI 
AU  - NING, LIJUAN 
AU  - LEI, YU 
AU  - ZHANG, XUEFEI 
AU  - WANG, ZHUYING 

TI  - Apigenin as a promising myocyte protectant against damage and degradation
T2  - BIOCELL

PY  - 2022
VL  - 46
IS  - 2
SN  - 1667-5746

AB  - Myocytes power the movement of all organs in the body. Damage to and degradation of myocytes causes
hypokinesia and muscle-related degenerative diseases. Apigenin, a kind of flavone, is being used to treat many
disorders. It exerts a host of different pharmacological activities, such as anti-inflammatory, anti-mutagenic,
cardioprotective, and antioxidant effects. Accordingly, apigenin is considered a promising candidate for myocyte
protection. In this review, we introduced the characteristics of apigenin. The means of apigenin protection of
myocytes as well as the mechanism were summarized and discussed. The protective effects can be classified into
proliferation-promoting, anti-inflammatory, atrophy-preventing, metabolism-increasing, and antioxidative effects.
Additionally, we provided some outlook on the valuable applications of apigenin in sports medicine, which eagerly
require further fundamental research.
KW  - Apigenin
KW  -  Myocyte
KW  -  Protectant
KW  -  Pharmacological activity

DO  - 10.32604/biocell.2021.015651