TY  - EJOU
AU  - QUAN, XIANGYU 
AU  - MA, XUETING 
AU  - LI, GUODONG 
AU  - FU, XUEQI 
AU  - LI, JIANGTAO 
AU  - ZENG, LINLIN 

TI  - Exploring exosomes to provide evidence for the treatment and prediction of Alzheimer’s disease
T2  - BIOCELL

PY  - 2023
VL  - 47
IS  - 10
SN  - 1667-5746

AB  - Exosomes are extracellular vesicles with a 30–150 nm diameter originating from endosomes. In recent years, scientists have regarded exosomes as an ideal small molecule carrier for the targeted treatment of Alzheimer’s disease (AD) across the blood-brain barrier due to their nanoscale size and low immunogenicity. A large amount of evidence shows that exosomes are rich in biomarkers, and it has been found that the changes in biomarker content in blood, cerebrospinal fluid, and urine are often associated with the onset of AD patients. In this paper, some recent advances in the use of exosomes in the treatment of AD are reviewed, and various exosome markers and some latest detection methods are summarized to provide some evidence for the detection or treatment of AD by exosomes.
KW  - Exosome; Alzheimer’s disease; Biomarker; Medical treatment; Medical forecast

DO  - 10.32604/biocell.2023.031226